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होम उत्पादCancer Treatment Steroids

CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex

CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex

    • CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex
    • CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex
  • CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex

    उत्पाद विवरण:

    Place of Origin: China
    ब्रांड नाम: Sendi
    प्रमाणन: SGS,ISO9001
    Model Number: Bicalutamide

    भुगतान & नौवहन नियमों:

    Minimum Order Quantity: 10 Grams
    मूल्य: 1.5 usd dollars per gram
    Packaging Details: Discreet and safe foil bag
    Delivery Time: Within 12hours after payment
    Payment Terms: West Union, T/T, Money Gram.,Bitcorn and bank transfer, D/P
    Supply Ability: 10000 Kg
    अब से संपर्क करें
    विस्तृत उत्पाद विवरण
    Name: Bicalutamide CAS: 90357-06-5
    Molecular Formula: C18H14F4N2O4S Description: White powder
    MW: 434.46 Assay: 99%
    Applications: Pharmaceutical raw materials Function: Hormone-refractory prostate cancer

     

     

    CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex

     

    Description 

     

    Name Bicalutamide
    Other name Casodex;N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide
    Application:With luteinising-hormone-releasing hormone (LHRH) analogues or surgical orchiectomy combined applied in the treatment of advanced prostate cancer.
    CAS 90357-06-5
    MF C18H14F4N2O4S
    Molecular Weight 430.37
    Appearance white powder
    Use Objective To evaluate the efficacy of bicalutamid ( casodex) in the treatment of hormone-refractory prostate cancer


    Package details:


    1kg/Aluminum foil bag
    1kg/ Aluminium Tin
    25kg/Drum
    25kg/ Aluminum Drum

    Delivery Time:Usually within 2 working days after confirming the payment.

    Shipping details: DHL; TNT; UPS or EMS

     

    Product Description

    Bicalutamid has a molecular weight of 430.37. The pKa' is approximately 12. Bicalutamid is a fine white to off white powder which is practically insoluble in water at 37°C (5 mg per 1000 mL), slightly soluble in chloroform and absolute ethanol, sparingly soluble in methanol, and soluble in acetone and tetrahydrofuran.CASODEX (bicalutamid) is a racemate with its antiandrogenic activity being almost exclusively exhibited by the R-enantiomer of bicalutamid; the S-enantiomer is essentially inactive.

     

    Applications

    Bicalutamid is used primarily in the treatment of early and advanced prostate cancer. It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone (GnRH) analogue or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), and as a monotherapy at a dosage of 150 mg/day for the treatment of stage C or D1 locally advanced prostate cancer (LAPC). Although effective in mPC and LAPC, bicalutamid is no longer indicated for the treatment of localized prostate cancer (LPC) due to negative findings in the Early Prostate Cancer (EPC) trial.

    Use

    How to use bicalutamid

    Read the Patient Information Leaflet if available from your pharmacist before you start taking bicalutamid and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

     

    Bicalutamid is used to treat prostate cancer that has spread to other areas of the body. It is used in combination with hormone treatment. This medication works by blocking the action of male hormones in the prostate, slowing growth of the tumors.

     

    ITems Specifications Test results
    Appearance White or off-white crystalline powder Conform
    Identification IR
    HPLC RT
    Conform
    Water ≤0.2% 0.02%
    Residue on ignition ≤0.10% 0.08%
    Particle size 90%<10um, 50%<5um Conform
    Heavy metals ≤10ppm Conform
    Related substances Des-fluoro analog1≤0.2% Negative
    2-Fluoro isomer2≤0.2% 0.17%
    Des hydroxyl analog3≤0.2% Negative
    Individual unspecified impurity≤0.1% 0.09%
    Total unspecified impurities≤0.3% 0.27%
    Total impurities≤0.5% 0.44%
    Assay 98.0%~102.0%(on dried basis) 99.8%
    Residual solvents Meet the requirements of ICH Q3C Conform


    6. Side effects

    The side effect profile of bicalutamid is highly sex-dependent. In women, the side effects of pure antiandrogens/NSAAs are minimal, and bicalutamid has been found to be very well-tolerated.

     

    In men however, due to androgen deprivation, a variety of side effects of varying severity may occur during bicalutamid treatment, with breast pain/tenderness and gynecomastia being the most commonand others including physical feminization and demasculinization in general (e.g., reduced body hair growth/density, decreased muscle mass and strength, changes

     

    in fat mass and distribution, and reduced penile length), hot flashes, sexual dysfunction (including loss of libido and erectile dysfunction), depression, fatigue, weakness, anemia, and decreased

     

    semen/ejaculate volume.General side effects of bicalutamid that may occur in either sex may include diarrhea, constipation, abdominal pain, nausea, dry skin, itching, and rash.The drug is well-tolerated at higher dosages (than the 50 mg/day dosage), with rare additional side effects
     

     

    Our commitment:

    1. Any inquiries will be replied within 12 hours.
    2. Dedication to quality, supply & service.
    3. Strictly on selecting raw materials.
    4. OEM/ODM Available.
    5. Reasonable & competitive price, fast lead time.
    6. Sample is available for your evaluation & Formulation development.
    7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
    8. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
    9. After-Sale Service:
    (1) International Authorized Third-Party Test For The Products You Demand.
    (2) 60 Days Warranty of quality of goods.

     

    More details:

    Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference.

    Payment: Western Union, MoneyGram We will supply the receiver's information or the bank account information for payment use.

    Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received.
    Every item will be shipped out in 1-2working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment.

    We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

     

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    CAS 90357-06-5 Prostate Cancer Treatment Steroids USP 36 Bicalutamide - Casodex 

    सम्पर्क करने का विवरण
    Shenzhen Sendi Biotechnology Co.Ltd.

    व्यक्ति से संपर्क करें: Demi

    दूरभाष: +8618123940985

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