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99% Pramipexole Dihydrochloride Treat Parkinson's Disease , CAS 104632-26-0

99% Pramipexole Dihydrochloride Treat Parkinson's Disease , CAS 104632-26-0

    • 99% Pramipexole Dihydrochloride Treat Parkinson's Disease , CAS 104632-26-0
    • 99% Pramipexole Dihydrochloride Treat Parkinson's Disease , CAS 104632-26-0
  • 99% Pramipexole Dihydrochloride Treat Parkinson's Disease , CAS 104632-26-0

    उत्पाद विवरण:

    Place of Origin: China
    ब्रांड नाम: Sendi
    प्रमाणन: SGS,ISO9001
    Model Number: Pramipexole Dihydrochloride

    भुगतान & नौवहन नियमों:

    Minimum Order Quantity: 10 Grams
    मूल्य: 1.5 usd dollars per gram
    Packaging Details: Discreet and safe foil bag
    Delivery Time: Within 12hours after payment
    Payment Terms: West Union, T/T, Money Gram.,Bitcorn and bank transfer, D/P
    Supply Ability: 10000 Kg
    अब से संपर्क करें
    विस्तृत उत्पाद विवरण
    Name: Pramipexole Dihydrochloride CAS: 104632-26-0
    MF: C10H17N3S Description: Off-White Solid
    Storage: Store in original container in a cool dark place. Functions: Treat Parkinson's Disease Drugs
    Assay: 99% Category: Pharmaceutical grade

    99% Pramipexole Dihydrochloride for Treat Parkinson's Disease CAS 104632-26-0

     

    Product name

     

    Pramipexole Dihydrochloride

     

    CAS NO.

    104632-26-0

     

    Synonyms

    1,4,5,6-tetrahydro-4,6-dioxo-s-triazine-2-carboxylicacid,potassiumsalt;5-azaoroticacid,potassiumsalt;kox;potassiumazaorotate;POTASSIUM OXONATE;POTASSIUM 4,6-DIHYDROXY-1,3,5-TRIAZINE-2-CARBOXYLATE;Potassium 1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylate;POTASSIUM ALLANTOXANATE
     

    Category

    Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
     

    Standard

    purity:>99%
     

    Appearance

    Off-White Solid

     

    Melting point

    288-290°C

     

    Storage

    Store in original container in a cool dark place.
     

    MF

    C10H17N3S

     

    Molecular Weight

    211.33

     

    Grade

     
    enterprise standard
     


    Description:
     

    Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. The primary purpose of this drug is in the treatment of Parkinson's disease. Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, although generics are also available. Mirapex is the most well known brand by Boehringer Ingelheim Pharmaceuticals.

     

    Along with treating Parkinson's, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.

     

    Specification of Pramipexole Dihydrochloride

     

     

    TEST ITEMS SPECIFICATION RESULTS
    Description White Crystalline Powder White Powder
    Identification Positive Positive
    Assay(by HPLC) 98.0~102.0% 98.64%
    Absorbance(E1cm) 465~495 482.5
    Melting Point 191~195°C 193.5~195.0°C
    Loss On Drying 0.5%max 0.19%
    Specific Rotation +288°~ +298° +290.2°
    Residue On Ignition 0.1%max 0.03%
    Related Substances Total:1.5%max <1.3%
      Single:0.5%max <0.4%
    Residue Solvents 0.2%max 0.10%
    Heavy Metals 20PPm max <10PPm
    Conclusion The specification conform with enterprise standard.

     
    Application :

    Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

    The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

    pramipexole Use:

     

    Treating the signs and symptoms of Parkinson disease. It is also used to treat restless legs syndrome (RLS). It may also be used for other conditions as determined by your doctor.

    Pramipexole is a dopamine agonist. Exactly how pramipexole works is not known. It may increase the action of certain chemical receptors in the brain.

    pramipexole side effects

    All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
    Abnormal dreams; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; stuffy nose; tiredness; trouble sleeping; weakness.


    Package details:
    1kg/Aluminum foil bag
    1kg/ Aluminium Tin
    25kg/Drum
    25kg/ Aluminum Drum

    Delivery Time:
    Usually within 2 working days after confirming the payment.
    Shipping details:
    DHL; TNT; UPS or EMS

     
     
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    Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received.
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    99% Pramipexole Dihydrochloride Treat Parkinson's Disease , CAS 104632-26-0

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